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Saturday, March 31, 2012

Postmenopausal Women Susceptible to Stroke

According to the Centers for Disease Control and Prevention United States over 800 thousand Americans each year have a stroke. During this study found eight out of every ten strokes, occur when blood clots, cholesterol is inhibited in growing blood vessels to the brain. Cholesterol consists of several lipids, or lipoproteins. While triglycerides are one type of lipoprotein, while others, including low-density lipoprotein (LDL) and high density lipoprotein (HDL). 
Stroke diagram. (Picture from: http://skokienet.org/)
Postmenopausal women, may be at higher risk of stroke than those not monopause. A study by researchers at NYU Langone Medical Center and colleagues found that traditional risk factors for stroke such as high cholesterol is not accurate to link the risk in postmenopausal women as previously thought. Instead, the researchers said, doctors should refocus their attention on triglyceride levels, to determine the highest risk of severe and fatal cardiovascular patients. "Every year, hundreds of thousands of people affected by stroke and there is tremendous emphasis on identifying people at increased risk," said lead author Jeffrey S Berger, MD, assistant professor of medicine and director of the Cardiovascular Thrombosis at the NYU School of Medicine part of NYU Langone Medical Center. 

The researchers analyzed data for the last 15 years, finds 90 thousand postmenopausal women had a stroke. The most interesting findings, according to Dr. Berger, is that high triglyceride levels, were significantly associated with the development of stroke. 

Even women who have high triglyceride levels, nearly twice as likely to suffer a stroke iskerriik. While women who have low triglyceride levels, more secure than a stroke. Surprisingly LDL cholesterol and total cholesterol, were not associated with stroke risk. Although they are very high cholesterol levels, in the medical community study. 

A question, is there a strong relationship between triglycerides and stroke in other populations is still unknown? "This is just the first step is very important. But that's not the end of the story," says Dr. Berger.

Associated with people with large waist size (fat), with high triglycerides are at increased risk of coronary heart disease, according to a study published in CMAJ (Canada Medical Association Journal) results are very significant. The concept of hypertriglyceridemic waist phenotype, no tangible connection with high triglyceride levels. 

Waist width and large, as a marker of metabolic abnormalities that could help spur an increased risk of coronary heart disease. CMAJ research on the type of hypertriglyceridemic waist, is useful to set cost-effective in screening to identify people at risk of type 2 diabetes and coronary heart disease. 21,787 research on men and women aged 45 to 79 years in Norfolk, England in 2011. 

Of the total sample of 1,295 men and 814 women, may develop coronary heart disease over a period of 8 to 10 years. Examples of studies of both men and women, which increased waist circumference (even without higher triglyceride levels) there are significant indications and triglycerides increased (even without higher waist circumference) appeared to increase the risk of coronary heart disease. An important finding of this study is that the combined presence of increased waist circumference and increased triglyceride levels associated with high risk of coronary heart disease.

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